Periactin (Cyproheptadine)

Periactin (Cyproheptadine)


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Active ingredient: Cyproheptadine

Dosage: 4mg

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What Is Periactin (Cyproheptadine)?

Periactin (cyproheptadine) is a medication primarily used as an antihistamine to alleviate allergy symptoms such as sneezing, itching, watery eyes, and runny nose. It is also effectively used to stimulate appetite in individuals who need to increase their food intake, particularly beneficial for patients undergoing treatments that affect their appetite or those suffering from eating disorders. The drug is available in a standard dosage of 4mg, which is prescribed based on the patient’s specific medical condition and response to treatment. It is important for users to follow the prescribed dosage carefully and adjust only under medical supervision to avoid potential side effects.

The active ingredient in Periactin is cyproheptadine hydrochloride. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. In addition to its antihistaminic effects, the medication’s ability to block serotonin receptors contributes to its effectiveness in stimulating appetite. The medication is especially useful for managing varied clinical conditions that require both suppression of allergic symptoms and appetite enhancement. This dual action makes this medication versatile in both pediatric and adult patient populations, addressing a broad spectrum of health issues effectively.

Frequently Asked Questions about Periactin (Cyproheptadine)

What are Periactin cyproheptadine hydrochloride tablets used for?

Periactin tablets are primarily used to treat allergy symptoms, appetite stimulation, and other conditions as prescribed by a healthcare provider. They effectively manage a range of allergic reactions by blocking the action of histamine. In addition to these uses, the drug is sometimes prescribed off-label for other medical conditions that benefit from its antihistamine properties.

How should Periactin be taken?

To take Periactin (Cyproheptadine) effectively, follow the instructions on your prescription label meticulously. Typically, it is prescribed to be taken two to three times a day, depending on your specific condition and response to the treatment. Swallow the tablets whole with a glass of water, and you can take them with or without food. It’s essential to take the tablet at evenly spaced intervals to maintain a consistent level of the medication in your body. Do not suddenly stop taking this drug without consulting your healthcare provider, as abrupt discontinuation can lead to a rebound of symptoms or adverse effects.

How much Periactin can I take?

The typical dosage of Periactin (Cyproheptadine) for adults is one 4mg tablet taken three times a day, but the exact dosage can vary based on individual needs and response to treatment. For children, the dosage is adjusted according to age and body weight. It’s crucial not to exceed the maximum recommended dosage of 20 mg per day for adults unless directed by a healthcare provider. Always follow your doctor’s instructions and consult them if you have any questions or concerns about your dosage.

What is the recommended dosage of Periactin (Cyproheptadine) for adults?

The recommended starting dosage for adults is one 4mg tablet three times a day, adjusted according to individual response and needs. It’s important to note that the maximum recommended dose should not exceed 20 mg per day. Regular follow-up with your healthcare provider is essential to monitor effectiveness and adjust dosages if necessaryю

What are the common side effects of Cyproheptadine?

Common side effects include:

  • Drowsiness
  • Dizziness
  • Blurred vision
  • Dry mouth
  • Constipation

If these effects persist or worsen, it is crucial to consult with your healthcare provider for possible adjustments to your treatment.

Is there a generic version of Periactin?

Yes, generic versions of Cyproheptadine are available, offering the same efficacy at a lower cost than the brand-name Periactin. These generics provide a cost-effective alternative for patients seeking treatment for allergies and appetite issues. Many patients find the generic versions more accessible, especially for long-term use.

How does Periactin (Cyproheptadine) help with appetite stimulation?

Periactin (Cyproheptadine) acts as an antihistamine that also has antiserotonergic properties, which can increase appetite, making it useful for conditions that require enhanced food intake. This effect makes it particularly valuable in treating patients who need to gain weight or improve their nutritional status. This mechanism is beneficial not only for those with chronic conditions but also for recovering patients who have experienced significant weight loss.

Can Cyproheptadine (Periactin) be used for delayed ejaculation?

Yes, Cyproheptadine has been used off-label to treat delayed ejaculation due to its properties that affect serotonin levels, but it should only be used under medical supervision. Discussions with a healthcare provider can ensure safe and appropriate usage for this condition. This application of the drug offers an alternative treatment path for patients unresponsive to conventional therapies.

Can Periactin be used to help with sleep?

Yes, cyproheptadine pills can be used off-label to help with sleep due to its sedative effects, which are a side effect of its antihistamine properties. While not primarily prescribed as a sleep aid, its ability to induce drowsiness makes it beneficial for patients who suffer from insomnia linked to allergies or stress. However, it is important to consult a healthcare provider before using Periactin for sleep to ensure it is appropriate for your specific health conditions

What is the classification of Periactin?

Cyproheptadine (the drug’s active ingredient) belongs to a class of medications known as first-generation antihistamines with additional antiserotonergic properties. These drugs are particularly effective due to their dual action against allergic reactions and serotonin-related disorders. Understanding this classification can help patients and healthcare providers decide if this is the right medication for their specific medical needs.

What does Periactin do to the body?

Periactin (Cyproheptadine) helps relieve allergy symptoms like sneezing, itching, and a runny nose by blocking histamine, a chemical in the body that triggers these reactions. Besides easing allergies, it also blocks serotonin, which can help increase appetite. This combination of effects not only helps manage allergic reactions but can also boost appetite and sometimes cause drowsiness. Overall, this drug is useful for treating various allergic conditions and appetite issues.

Where can I find more information about Periactin (Cyproheptadine)?

For more comprehensive details on Periactin (Cyproheptadine), click here. You may also consult your pharmacist or healthcare provider for further information.


This document does not include all information about this medication and should not replace the medication guide, a consultation with a pharmacist, or advice from your healthcare provider. For the complete medication guide or additional questions, please contact your pharmacist.

by Emily A. Rosten, MD
Medically Reviewed by Dr. Peter Thura
Last Updated: June 17, 2024

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